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Minocycline Q&A

May 21, 2012 By: kajay Category: Minocycline

After posting several times in various groups about my taking Minocycline, I received several emails asking for information about Minocycline. This gives me an opportunity to clarify a couple of points. I have included the contents of one such excellent email and will use it to answer the questions I have received:

Q: I was wondering about the minocycline. Have you already started to take this?

A: Yes. One month in.

Q: You are female, correct?

A: Yes.

Q: I have been unsuccessful in finding an MD to treat my Morgellons. However…

…using dewormers, Ketoconazole, Flagyl, and various antibiotics, as well as baths and herbs, has helped. I recently learned about Minocycline and that it might be a more appropriate antibiotic for Spirochetes. However, I could not find any long-term or definitive research about the drug. What I did find was a study about how this antibiotic may be more appropriate for neurological Spirochetes because it goes readily to the brain. However, the study that I read said that because of this, it was more likely to cause nervous system or brain side effects. I think the side effects mentioned were dizziness, nausea, and confusion. These studies suggest that women experience these side effects more commonly than do men. I have considered trying the Minocycline. Since reading the study, have been reluctant to do so. So I was wondering if you could enlighten me on your experience thus far with this antibiotic and the dosage and frequency you are taking.

A: I take 100mg daily, at least an hour before or after consuming food or supplements containing calcium.

Q: What side effects are you suffering from the Minocycline?

A: Yeast infection and increased herxing. Yeast infection – I have experienced only mild yeast infection symptoms which, because I have been using Gordon’s F-Zymes for 14 months and did not have a yeast problem going into my Minocycline treatment, I easily knocked out (hope it remains easy) by drinking a glass of warm water with a teaspoon of baking soda in it. Herxing – I was already experiencing significant shedding and occasional localized intense but brief and generally nonrecurring pain spikes throughout my body. The herxing was ongoing due to the F-zymes, which I have continued after adding Minocycline to my routine. However, the Minocycline immediately increased the shedding, which I consider to be a herx since it is clearly a die-off. I have also experienced an increase in the rash on my skin which I remedy by using the F-Zyme spray and “rubbing out” what has surfaced and is acting up on the surface, causing the rash symptoms.

Q: Can you tell me more about the Minocycline?

A: Here is one of several online Material Safety Data Sheets (MSDSs) that I found for the Minocycline: http://www.drugbank.ca/drugs/DB01017 Here is an extract from this link of the information I think best explain why my LLMD prescribed Minocycline. I have not listed side effects as you already did that for us: Indication For the treatment of infections caused by susceptible strains of microorganisms, such as Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsial pox and tick fevers caused by Rickettsiae, upper respiratory tract infections caused by Streptococcus pneumoniae and for the treatment of asymptomatic carriers of Neisseria meningitidis. Pharmacodynamics Minocycline, the most lipid soluble and most active tetracycline antibiotic, is, like doxycycline, a long-acting tetracycline. Minocycline’s effects are related to the inhibition of protein synthesis. Although minocycline’s broader spectrum of activity, compared to other members of the group, includes activity against Neisseria meningitidis, its use as a prophylaxis (preventive measure) is no longer recommended due to side effects (dizziness and vertigo)…The neuroprotective action of minocycline may include its inhibitory effect on 5-lipoxygenase, an inflammatory enzyme associated with brain aging. Mechanism of action Minocycline passes directly through the lipid bilayer or passively diffuses through porin channels in the bacterial membrane. Tetracyclines like minocycline bind to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. Absorption Rapidly absorbed from the gastrointestinal tract and absorption is not significantly impaired by ingestion of food or milk. Oral bioavailability is 100%.

Q: Why do you suppose women seem to have more or more severe side effects?

A: As for your gender question, I would suggest that studies that reveal a gender difference were not necessarily conducted for the purpose of identifying the reason for the difference. They might be conducted only to see if there is one, the reason being that the tests to determine a distinction would be much less extensive than those to determine a reason.

 

 

3 Comments to “Minocycline Q&A”


  1. Vivian Leese says:

    Thanks for the info on Minocycline. My dermatologist (!)’ who cares so much, had me on Doxycycline 200mg per day. I could not tolerate the nausea, but it kept the worms at bay and the smaller insect-types were completely gone. I just started the Mino. Hope it does the trick.

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  2. Vivian Leese says:

    December 5, 2013

    Hurray for Minocycline! My dermatologist ( !), bless his heart, who takes SUCH good care of me, prescribed 50mg, twice a day of Minocycline. I have been taking it since October 1. I have no nausea or vomiting, as I did with Doxycycline. It keeps the worms from swarming about 95 percent of the time. What a blessing! it does little during full moon phases. Nothing works then. The worms just hang out in my nose and around my mouth and eyes. I don’t hear from them much, but if I do, I apply some hydrogen peroxide to two Q-Tips and wash my nostrils out. Those guys will shortly be hanging from inside my nose, dead as a door nail. (Sorry for being gross). Listerine Cool Mint mouthwash works just as well. They both burn, but that doesn’t last long.
    The Minocycline keeps most critters at bay, too. I say most. My critter load is in my mouth and between my teeth and beneath my facial skin. The worst places! I haven’t found my FAV product yet that they hate.
    Anyone?
    I have the strangest artifacts that are oral in origin, too.
    As we say in The South, y’all come back to see us!

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  3. Thank you, Vivian. Not gross to me – you are describing victory, and every victory, no matter how small, feels VICTORIOUS, lol.

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